The laboratory of Alexey Ivanov, Ph.D., focuses on mechanisms that regulate gene expression with a special emphasis on how the DNA-packaging structure of chromatin is regulated during cellular processes. The laboratory seeks to define the biochemical and molecular mechanisms that govern the normal silencing of genes during development and homeostasis, as well as disruptions of these governing mechanisms during tumor initiation and progression.
The lab works closely with the Cancer Cell Biology program. The West Virginia IDeA network of Biomedical Research (WV-INBRE), The HSC Office of Research and Graduate Education and the MBRCC Summer Research Fellowship Program to bring undergradute, medical and graduate students to the lab to conduct in research. Students are given the opportunity to perform biomedical research in the lab during the summer. The lab also works closely with the Alexander B. Osborn Hematopoietic Malignancy and Transplantation Research Program at the Center.