WVU cancer researcher and Assistant Professor of Pharmaceutical Sciences Wei Du, MD, PhD, teamed up with researchers from Cincinnati Children’s Hospital Medical Center to focus on improving outcomes and reducing side effects of traditional stem cell transplant. Their work was recently published in Leukemia, one of the top journals in hematology.
The studies identify an innovative drug that targets Cdc42, a member of one of the Rho GTPase family, which increases bone marrow accessibility and therefore improves stem cell transplant outcome. This project is an extension of previous research in the field of Rho GTPase family in hematopoiesis and is intended to address the urgent and important need for stem cell transplantation. Dr. Du’s work offers a novel preparative regimen for stem cell transplantation in treating bone marrow failure and other blood diseases. They are currently working on establishing improved methods for blood stem cell harvest and transplantation that could significantly impact future stem cell therapies for patients with leukemia and other blood cancers.
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Two Studies Describe Improved Approach to Bone Marrow Transplant - Cincinnati Children's Newsroom
David McDonald, 55, of Morgantown, didn’t expect a cancer diagnosis when he brought up some symptoms he had been having during a doctor’s appointment for stomach pain. He mentioned to his doctor that he had been having some rectal bleeding, and his family doctor sent him for further tests to find the cause.
School of Public Health students are collecting items for an Infant/Toddler Supplies Drive through April 17 to benefit The Shack Neighborhood House.
This year marks the 25th anniversary for the program which starts on Monday, April 15 and runs through Tuesday, July 23. “Last year we had over 4,700 people participate,” said Dave Harshbarger, wellness manager for WVU Medicine making Walk 100 Miles in 100 Days® the largest exercise program in the state.