Defense Health Program, Funding Opportunities for Fiscal Year 2017

Department of Defense Peer Reviewed Medical Research Program

Defense Health Program

Department of Defense Peer Reviewed Medical Research Program

Funding Opportunities for Fiscal Year 2017 (FY17)

FY17 PRMRP Program Announcements and General Application Instructions for the following award mechanisms are posted on Grants.gov.

As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency (DHA) J9, Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).

Congressionally Directed Topic Areas. All applications submitted to the PRMRP must address at least one of the FY17 PRMRP Congressionally directed topic areas. As of the release date of this pre-announcement, the FY17 PRMRP Topic Areas have not been finalized. This pre-announcement should not be construed as an obligation by the Government to include any of these Topic Areas or others in the FY17 PRMRP. The potential FY17 PRMRP Topic Areas are:

  • Acute Lung Injury
  • Antimicrobial Resistance
  • Arthritis
  • Burn Pit Exposure
  • Chronic Migraine and Post-Traumatic Headache
  • Congenital Heart Disease
  • Constrictive Bronchiolitis
  • Diabetes
  • Diarrheal Diseases
  • Dystonia
  • Early Trauma Thermal Regulation
  • Eating Disorders
  • Emerging Infectious Diseases
  • Epidermolysis Bullosa
  • Focal Segmental Glomerulosclerosis
  • Fragile X Syndrome
  • Guillain-Barré Syndrome
  • Hepatitis B and C
  • Hereditary Angioedema
  • Hydrocephalus
  • Immunomonitoring of Intestinal Implants
  • Inflammatory Bowel Diseases
  • Influenza
  • Integrative Medicine
  • Interstitial Cystitis
  • Malaria
  • Metals Toxicology
  • Mitochondrial Disease
  • Musculoskeletal Disorders
  • Nanomaterials for Bone Regeneration
  • Non-Opioid Pain Management
  • Pancreatitis
  • Pathogen-Inactivated Dried Cryoprecipitate
  • Polycystic Kidney Disease
  • Post-Traumatic Osteoarthritis
  • Pulmonary Fibrosis
  • Respiratory Health
  • Rett Syndrome
  • Rheumatoid Arthritis
  • Scleroderma
  • Sleep Disorders
  • Spinal Muscular Atrophy
  • Sustained-Release Drug Delivery
  • Tinnitus
  • Tuberculosis
  • Vaccine Development for Infectious Disease
  • Vascular Malformations
  • Women’s Heart Disease

Military Relevance: Relevance to the healthcare needs of the military Service members, Veterans, and beneficiaries is a key feature of each FY17 PRMRP award mechanism.

Clinical Trial Award- Preapplication due July 20, 2017

· Assistant Professor level or above (or equivalent)

· Preproposal submission is required; application submission is by invitation only.

· Supports the rapid implementation of clinical trials of novel interventions with the potential to have a significant impact on patient care in the topic area(s) of interest.

· Proposed projects may range from small proof-of-concept trials through large-scale, definitive trials.

· Investigational New Drug or Investigational Device Exemption applications, if needed, should be submitted to the Food and Drug Administration by the PRMRP Grants.gov application submission deadline.

· Funding limit not defined; requested funding must be appropriate for the scope of work proposed

· Maximum period of performance is 4 years

Discovery Award – Letter of Intent due July 19, 2017

· All Investigators

· Supports the exploration of a highly innovative new concept or untested theory.

· Not intended to support the logical progression of an already established line of questioning.

· Clinical trials will not be funded.

· Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborators, and their organization(s).

· Maximum of $200,000 for direct costs (plus indirect costs)

· Maximum period of performance is 18 months

Focused Program Award – Preapplication due July 20, 2017

· Full Professor level or above (or equivalent)

· Preproposal submission is required; application submission is by invitation only.

· Supports a synergistic, multidisciplinary research program of at least four distinct but complementary projects addressing an overarching goal.

· Projects should work together to answer critical questions, resolve differing hypotheses, and translate laboratory findings to clinical applications.

· Projects may range from exploratory/ hypothesis-developing through small-scale clinical trials that together will address the overarching goal/question.

· Research team of highly qualified, multidisciplinary project leaders should be led by a PI with demonstrated success in directing large, focused projects.

· Maximum of $10 million for total costs (includes direct and indirect costs)

· Maximum period of performance is 4 years

 

Investigator-Initiated Research Award – Preapplication due July 13, 2017

  • Assistant Professor level or above (or equivalent)

· Preproposal submission is required; application submission is by invitation only.

· Supports research that will make an original and important contribution to the field of research or patient care in the topic area(s) of interest.

· Partnering PI Option available.

  • Clinical trials will not be funded.

· Maximum of $1.2 million for direct costs (plus indirect costs)

· Maximum of $1.5 million for direct costs (plus indirect costs) for applications including a Partnering PI Option

  • Maximum period of performance is 3 years

Technology/ Therapeutic Development Award – Preapplication due July 13, 201

  • Assistant Professor level or above (or equivalent)

· Supports the translation of promising preclinical findings into clinical applications for prevention, detection, diagnosis, treatment, or quality of life.

· Product-oriented (e.g., device, drug, clinical guidelines). The product(s) to be developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product.

· Clinical trials will not be funded.

  • Preproposal submission is required; application submission is by invitation only.

· Maximum of $3.0 million for direct costs (plus indirect costs)

· Maximum period of performance is 3 years

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism can also be found on Grants.gov. A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

Applications must be submitted through the federal government’s single-entry portal, Grants.gov. For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the PRMRP or other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).

 

Point of Contact:

Help Desk

301-682-5507

help@eBrap.org

 

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