Services

IVIS® Lumina II Imaging

AMIF offers real time in vivo optical imaging using the IVIS® Lumina II Imaging System.  This system allows researchers to perform non-invasive imaging to monitor and record cellular and genetic activity within an animal using light producing optical reporters such as luciferase and fluorescent proteins, fluorescent dyes and conjugates. Genes encoding luciferase and fluorescent proteins can be engineered into cells (e.g., cancer cell lines and infectious disease agents) and animals (transgenic mice) to enable them to produce light that can then be visualized through the tissues of a live animal using the IVIS Lumina II and the Living Image Software.

This highly sensitive dual bioluminescence and fluorescence imaging system allows significantly fewer animals to be used due to the non-invasive nature of the system, the generation of superior data, and better biostatistics.

In vivo imaging using the IVIS Lumina II has applications in many different disciplines such as Oncology, Chemical Toxicology, Inflammation, Infectious Disease, Drug Discovery, etc.

 

Vevo® 2100 Micro-Ultrasound Imaging

AMIF also offers ultrasound imaging using the Vevo 2100® Micro-Imaging System. The Vevo 2100 (VisualSonics) provides the ability to visualize anatomical structures and hemodynamic functions in vivo and longitudinally in a non-invasive manner. All areas of research involving phenotypic expression within the small animal models can apply the high-resolution, real-time visualization benefits of the Vevo system.

 

Applications and techniques include cardiovascular, cancer biology, neurobiology, developmental biology, gene delivery, nephrology, hematology, ophthalmology, reproductive biology, rheumatology and musculoskeletal, regenerative medicine and stem cell, contrast imaging, image-guided injection, blood flow analysis, and 3D visualization and measurement.

Imaging will be offered for mice and rats and will be done by AMIF personnel. Since imaging will be done on live animals within a room in the animal quarters, we cannot offer user operation at this time.

Please see the Operations section for information on how to get a project started, or contact us.